Fluconazole side effects include which rare serious event?

Fluconazole side effects include which rare serious event?

• A. Rare liver damage
• B. Kidney injury
• C. Hearing loss
• D. Seizures

Answer: (A)

Rare but serious liver injury is a key risk with fluconazole. Although most people tolerate this antifungal well, hepatotoxicity can occur and may manifest as fatigue, nausea, abdominal pain, jaundice, dark urine, or elevated liver enzymes. Because the liver processes the drug, those with preexisting liver disease or those on high-dose or long-term therapy are at higher risk, so monitoring liver function during extended treatment is advised. This is why liver damage is the correct option. Kidney injury is not a typical or well-documented effect of fluconazole, and hearing loss or seizures are not standard adverse effects associated with this medication.

Rare but serious liver injury is a key risk with fluconazole. Although most people tolerate this antifungal well, hepatotoxicity can occur and may manifest as fatigue, nausea, abdominal pain, jaundice, dark urine, or elevated liver enzymes. Because the liver processes the drug, those with preexisting liver disease or those on high-dose or long-term therapy are at higher risk, so monitoring liver function during extended treatment is advised. This is why liver damage is the correct option. Kidney injury is not a typical or well-documented effect of fluconazole, and hearing loss or seizures are not standard adverse effects associated with this medication.